GADD45α (clone 6C3-G3-E9), anti-transfected

Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.(provided by RefSeq, Dec 2010).

Synonyms: DDIT1, GADD45

Cellular Location: Nucleus

Immunogen:
Purified recombinant human GADD45 α protein expressed in E.coli

Gene Symbol: GADD45α

Gene ID: 1647

Swiss prot: P24522

Calculated MW: 22kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.