GADD45A polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7294
Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
DDIT 1, DDIT-1, DDIT1, DNA damage inducible transcript 1, DNA damage-inducible transcript 1 protein, GA45A_HUMAN, GADD45, GADD45A, Growth arrest and DNA damage inducible 45 alpha, Growth arrest and DNA damage inducible alpha, Growth arrest and DNA damage-inducible protein GADD45 alpha,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: GADD45A polyclonal antibody detects endogenous levels of GADD45A protein.
Immunogen:
Recombinant full length Human GADD45A.
MW: ~18 kDa
Swis Prot.: P24522
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
DDIT 1, DDIT-1, DDIT1, DNA damage inducible transcript 1, DNA damage-inducible transcript 1 protein, GA45A_HUMAN, GADD45, GADD45A, Growth arrest and DNA damage inducible 45 alpha, Growth arrest and DNA damage inducible alpha, Growth arrest and DNA damage-inducible protein GADD45 alpha,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: GADD45A polyclonal antibody detects endogenous levels of GADD45A protein.
Immunogen:
Recombinant full length Human GADD45A.
MW: ~18 kDa
Swis Prot.: P24522
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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