GADD45GIP1 Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20586a
Background:
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Other Names:
Growth arrest and DNA damage-inducible proteins-interacting protein 1, 39S ribosomal protein L59, mitochondrial, MRP-L59, CKII beta-associating protein, CR6-interacting factor 1, CRIF1, Papillomavirus L2-interacting nuclear protein 1, PLINP, PLINP-1, p53-responsive gene 6 protein, GADD45GIP1, MRPL59, PLINP1, PRG6
Target/Specificity:
The synthetic peptide sequence is selected from aa 33-45 of HUMAN GADD45GIP1
Gene Name: GADD45GIP1
Gene ID: 90480
Primary Accession: Q8TAE8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Other Names:
Growth arrest and DNA damage-inducible proteins-interacting protein 1, 39S ribosomal protein L59, mitochondrial, MRP-L59, CKII beta-associating protein, CR6-interacting factor 1, CRIF1, Papillomavirus L2-interacting nuclear protein 1, PLINP, PLINP-1, p53-responsive gene 6 protein, GADD45GIP1, MRPL59, PLINP1, PRG6
Target/Specificity:
The synthetic peptide sequence is selected from aa 33-45 of HUMAN GADD45GIP1
Gene Name: GADD45GIP1
Gene ID: 90480
Primary Accession: Q8TAE8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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