Gai2 polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV10194-100
Catalog Number: AC-ABV10194-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβg subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.
Other Names:
guanine nucleotide binding protein G, GNAI2B, guanine nucleotide binding protein
Primary Accession: P04899
Other Accession: AAM12620
Gene Name: GNAI2
Gene ID: 2771
Concentration (mg/ml): 0.5 mg/ml
Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβg subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.
Other Names:
guanine nucleotide binding protein G, GNAI2B, guanine nucleotide binding protein
Primary Accession: P04899
Other Accession: AAM12620
Gene Name: GNAI2
Gene ID: 2771
Concentration (mg/ml): 0.5 mg/ml
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