GAK Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES2393
Catalog Number: ELK-ES2393
Reactivity: Human, Mouse
Applications: WB, IHC-p, IF, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse
Applications: WB, IHC-p, IF, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Alternative Names:
GAK, Cyclin-G-associated kinase
Immunogen: The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 144
GeneID: GAK
Storage: -20°C/1 year
NOTE: For Research Use Only
cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Alternative Names:
GAK, Cyclin-G-associated kinase
Immunogen: The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 144
GeneID: GAK
Storage: -20°C/1 year
NOTE: For Research Use Only
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