GAK polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP8061b
Catalog Number: AC-AP8061b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3949/3950
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3949/3950
Applications: WB, IHC-P
Datasheet
Request Information
Background:
GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.
Other Names:
Cyclin-G-associated kinase, GAK
Target/Specificity:
This GAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1140-1170 amino acids from the C-terminal region of human GAK.
Antigen Region:
1140-1170
Antigen Type: Synthetic Peptide
Gene Name: GAK (HGNC:4113)
Gene ID: 2580
Primary Accession: O14976
NCBI Accession: NP_005246.2
Other Accession: P97874; Q6P490
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.
Other Names:
Cyclin-G-associated kinase, GAK
Target/Specificity:
This GAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1140-1170 amino acids from the C-terminal region of human GAK.
Antigen Region:
1140-1170
Antigen Type: Synthetic Peptide
Gene Name: GAK (HGNC:4113)
Gene ID: 2580
Primary Accession: O14976
NCBI Accession: NP_005246.2
Other Accession: P97874; Q6P490
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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