Galectin-1 / Human Placental Lactogen (hPL) (clone GAL1/1831), anti-human
€0.00
In stock
SKU
AC-AH13361
Catalog Number: AC-AH13361
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: GAL1/1831
Applications: WB, IHC-P, IF, FC, E
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: GAL1/1831
Applications: WB, IHC-P, IF, FC, E
Datasheet
Request Information
Background:
Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Other Names:
14kDa laminin-binding protein; Beta-galactoside-binding lectin L-14-I; Gal-1; GAL1; Galaptin; Galectin-1; HLBP14; HPL; Lactose-binding lectin 1; Lect14; Lectin galactoside-binding soluble 1; LGALS1; MAPK activating protein MP12; S-Lac lectin 1
Antigen Type:
Recombinant protein
Gene Name: LGALS1 (HGNC:6561)
Gene ID: 3956
Primary Accession: P09382
Other Accession: 445351
Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Other Names:
14kDa laminin-binding protein; Beta-galactoside-binding lectin L-14-I; Gal-1; GAL1; Galaptin; Galectin-1; HLBP14; HPL; Lactose-binding lectin 1; Lect14; Lectin galactoside-binding soluble 1; LGALS1; MAPK activating protein MP12; S-Lac lectin 1
Antigen Type:
Recombinant protein
Gene Name: LGALS1 (HGNC:6561)
Gene ID: 3956
Primary Accession: P09382
Other Accession: 445351
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