Galectin-13 (GAL13) / Placental Protein 13 (PP13) (clone PP13/1165), anti-human
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SKU
AC-AH13283
Catalog Number: AC-AH13283
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: PP13/1165
Applications: IHC-P, IF, FC, E
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: PP13/1165
Applications: IHC-P, IF, FC, E
Datasheet
Request Information
Background:
It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble β-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
Other Names:
Gal-13; GAL13; Galactoside-binding soluble lectin 13; Galectin-13; Galectin13; Lectin galactoside binding soluble 13; LGALS13; PLAC8; Placental protein 13 (PP13); Placental tissue protein 13
Antigen Type:
Recombinant protein
Gene Name: LGALS13
Gene ID: 29124
Primary Accession: Q9UHV8
Other Accession: 23671
It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble β-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
Other Names:
Gal-13; GAL13; Galactoside-binding soluble lectin 13; Galectin-13; Galectin13; Lectin galactoside binding soluble 13; LGALS13; PLAC8; Placental protein 13 (PP13); Placental tissue protein 13
Antigen Type:
Recombinant protein
Gene Name: LGALS13
Gene ID: 29124
Primary Accession: Q9UHV8
Other Accession: 23671
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