Galectin 3 Polyclonal Antibody

Background:
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell, being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation, apoptosis, angiogenesis, immune response, neoplastic transformation and metastasis .

Research Area: Cancer, Cell Biology, Neuroscience

Synonyms:
35 kDa lectin, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, CBP 35, CBP35, Gal-3, GAL3, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, Galectin 3 internal gene, included, Galectin-3, Galectin3, GALIG, GBP, IgE binding protein, IgE-binding protein, L 31, L 34, L-31, L-34 galactoside-binding lectin, L31, Laminin-binding protein, Lectin L-29, Lectin, galactose binding, soluble 3, LEG3, LGALS2, LGALS3, MAC 2 antigen, Mac-2, Mac-2 antigen, MAC2, Macrophage galactose-specific lectin, MGC105387

Immunogen: Recombinant protein corresponding to Mouse mac2

Swissprot: P17931,P08699,P16110

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.52 mg/mL
Dilution: IHC 1:200-1:800

Storage:
Store at -20°C. Avoid freeze / thaw cycles.