Galectin 7 polyclonal, anti-human

Background:
Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galectin-7, expressed mainly in stratified squamous epithelium, is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. The galectin-7 gene maps to chromosome 19. Mainly expressed in stratified squamous epithelium.

Alternative Name:
Gal-7, LGALS7, PIG1, LGALS7B, Gal-7, GAL7, Galectin 7B, Galectin-7, HKL-14, Human keratinocyte lectin 14, Keratinocyte lectin 14, Lectin galactoside binding soluble 7, Lectin, galactoside binding, soluble, 7B, LEG7, LGALS7, LGALS7A, LGALS7B, P53 induced protein 1, p53-induced gene 1 protein, Pi7, PIG1, TP53I1,

Application Dilution:
ICC:1:50-1:200
IHC:1:100-1:300
WB:1:500-1:1,000
IP:1:10-1:50

Specificity: Galectin 7 polyclonal antibody detects endogenous levels of Galectin 7 protein.

Immunogen:
Recombinant protein

MW: 15 kDa

Swiss-Prot: P47929(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.