GALM polyclonal, anti-human
€305.00
In stock
SKU
BS61444
Background:
Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts ∫-aldose to å-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of ∫-D-galactose to å-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.
Alternative Name:
Aldose 1-epimerase, Galactose mutarotase, GALM
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: GALM polyclonal antibody detects endogenous levels of GALM protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 10-55 of Human GALM .
MW: ~ 37 kDa
Swis Prot.: Q96C23
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts ∫-aldose to å-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of ∫-D-galactose to å-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.
Alternative Name:
Aldose 1-epimerase, Galactose mutarotase, GALM
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: GALM polyclonal antibody detects endogenous levels of GALM protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 10-55 of Human GALM .
MW: ~ 37 kDa
Swis Prot.: Q96C23
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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