gamma Catenin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Junction plakoglobin(JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to β-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Description:
Rabbit IgG polyclonal antibody for Junction plakoglobin (JUP) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Synonyms:
ARVD 12 antibody, ARVD12 antibody, Catenin (cadherin associated protein) gamma 80kDa antibody, Catenin (cadherin associated protein), gamma 80kDa antibody, catenin (cadherin-associated protein) gamma (80kD) antibody, Catenin gamma 80kDa antibody, Catenin gamma antibody, CTNNG antibody, Desmoplakin 3 antibody, Desmoplakin III antibody, Desmoplakin-3 antibody, Desmoplakin3 antibody, DesmoplakinIII antibody, DP 3 antibody, DP III antibody, DP3 antibody, DPIII antibody, Gamma catenin antibody, Junction plakoglobin antibody, JUP antibody, OTTHUMP00000164732 antibody, OTTHUMP00000164735 antibody, OTTHUMP00000164738 antibody, PDGB antibody, PKGB antibody, PLAK_HUMAN antibody, PLAKOGLOBIN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.