Gamma-synuclein (clone 1H10D2), anti-human
€421.00
In stock
SKU
252664
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Nervous and Sensory Systems
Description:
SNCG (Gamma-synuclein) is a 127-amino acid protein (~14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical and breast cancer, but rarely expressed in tumor-matched non-neoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Alternate Names: Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, BCSG1, PERSYN, PRSN, SNCG
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: O76070
Antigen: Purified recombinant fragment of SNCG expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
SNCG (Gamma-synuclein) is a 127-amino acid protein (~14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical and breast cancer, but rarely expressed in tumor-matched non-neoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Alternate Names: Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, BCSG1, PERSYN, PRSN, SNCG
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: O76070
Antigen: Purified recombinant fragment of SNCG expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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