gamma Tubulin Monoclonal Antibody

Background:
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
TUBG1 (Tubulin Gamma 1) is a Protein Coding gene. Diseases associated with TUBG1 include Cortical Dysplasia, Complex, With Other Brain Malformations 4 and Reducing Body Myopathy. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBG2.

Research Area: Signal Transduction

Synonyms:
Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1, TBG1, TUBG, TUBG1, TUBGCP1, Tubulin gamma-1 chain, Tubulin, gamma 1, Tubulin, gamma polypeptide

Immunogen: Synthetic Peptide of Gamma Tubulin

Swissprot: P23258
Observed MW: 50 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:1000-2000, IHC 1:100-200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.