GAMT Polyclonal Antibody

Background:
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
GAMT, CCDS2, HEL-S-20, PIG2, TP53I2

Immunogen: Recombinant fusion protein of human GAMT (NP_000147.1).

Swissprot: Q14353
Gene ID: 2593

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.