GANAB Polyclonal Antibody

Background:
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Alpha glucosidase II alpha subunit, Alpha-glucosidase 2, G2AN, GANAB, GANAB, Glu II, Glucosidase alpha neutral AB, Glucosidase II alpha, Glucosidase II subunit alpha, GluII, KIAA0088, Neutral alpha glucosidase AB, Neutral alpha glucosidase AB precursor, Neutral alpha-glucosidase AB

Immunogen: Synthetic peptide of human GANAB

Swissprot: Q14697
Gene Accession: NP938148

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:2000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.