GAP-43 polyclonal, anti-rat

Quantity: 100 µl

Background:
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms:
GAP43, B-50, PP46

Isotype: Rabbit Polyclonal

Immunogen:
Synthetic GAP-43 (aa 221-226) conjugated to BSA

Form: Serum containing 0.1% sodium azide

Specificity:
The antiserum was raised against a synthetic C-terminus peptide of GAP-43. Absorption with 10-100 ?g GAP-43 per ml diluted antiserum abolishes the staining.

Reactivity: rat

Applications: Immunofluorescence, Immunohistochemistry, suitable for frozen sections

Working DIlution: 1:20 to 1:40

Positive Control:
Rat duodenum

Storage: 2-8C for immediate use, or at -20C (aliquot)

References:
- Botchkarev, VA et al. (1997) J. Comp. Neurol. 385: 379-395