GAPDH polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Glyceraldehyde-3-phosphate dehydrogenase catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide(NAD). The enzyme is though to be a tetramer of identical chains. Several highly homologous glyceraldehyde-3-phosphate dehydrogenase(GAPD)-related sequences have been identified previously in human DNA by Southern blot analysis. Protein studies have identified only a single expressed locus for this major glycolytic enzyme, and this maps to chromosome 12p13. Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) is a critical regulator of CICD, it mediates an elevation in glycolysis and enhanced autophagy that cooperate to protect cells from CICD.

Description:
Rabbit IgG polyclonal antibody for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Aging associated gene 9 protein antibody, G3P_HUMAN antibody, G3PD antibody, G3PDH antibody, GAPD antibody, GAPDH antibody, Glyceraldehyde 3 phosphate dehydrogenase antibody, Glyceraldehyde 3 phosphate dehydrogenase liver antibody, Glyceraldehyde 3 phosphate dehydrogenase muscle antibody, Glyceraldehyde-3-phosphate dehydrogenase antibody, MGC88685 antibody, OCAS p38 component antibody, OCT1 coactivator in S phase 38 KD Component antibody, Peptidyl-cysteine S-nitrosylase GAPDH antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human GAPDH (320-335aa YSNRVVDLMAHMASKE), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.