GARS Polyclonal Antibody

Background:
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
AP 4 A synthetase, Charcot Marie Tooth neuropathy 2D, Charcot Marie Tooth neuropathy neuronal type D, CMT2D , Diadenosine tetraphosphate synthetase, DSMAV , EC 6.1.1.14, Glycine tRNA ligase, Glycyl tRNA synthetase, GlyRS , HMN5, SMAD1

Immunogen: Fusion protein of human GARS

Swissprot: P41250
Gene Accession: BC000065

Calculated MW: 83 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.