GARS Polyclonal Antibody

Background:
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1

Immunogen: Recombinant fusion protein of human GARS (NP_002038.2).

Swissprot: P41250
Gene ID: 2617

Calculated MW: 83 kDa
Observed MW: 83 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:4000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.