GAS2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6155
Background:
Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells.
Alternative Name:
GAS 2, GAS-2, Gas2, GAS2, Growth arrest specific 2, Growth arrest specific protein 2, Growth arrest-specific protein 2,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GAS2 polyclonal antibody detects endogenous levels of GAS2 protein.
Immunogen:
Recombinant full length Human GAS2.
MW: ~ 35 kDa
Swis Prot.: O43903
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells.
Alternative Name:
GAS 2, GAS-2, Gas2, GAS2, Growth arrest specific 2, Growth arrest specific protein 2, Growth arrest-specific protein 2,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GAS2 polyclonal antibody detects endogenous levels of GAS2 protein.
Immunogen:
Recombinant full length Human GAS2.
MW: ~ 35 kDa
Swis Prot.: O43903
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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