GAS41 polyclonal antibody, anti-human, mouse

Background:
The protein encoded by YEATS4 (YEATS domain containing 4) is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. YEATS4 has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: YEATS4, GAS41, YEATS domain-containing protein 4, Glioma-amplified sequence 41, Gas41, NuMA-binding protein 1, NuBI-1, NuBI1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year