Gasdermin-E polyclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AP22465a
Catalog Number: AC-AP22465a
Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03173
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03173
Applications: WB
Datasheet
Request Information
Background:
[Gasdermin-E]: Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis (PubMed:27281216, PubMed:28459430, PubMed:33852854, PubMed:35594856, PubMed:36607699). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:28459430).
Other Names:
Gasdermin-E, Inversely correlated with estrogen receptor expression 1, ICERE-1, Non-syndromic hearing impairment protein 5, Gasdermin-E, N-terminal, GSDME-NT, Gasdermin-E, C-terminal, GSDME-CT, GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}
Gene ID: 1687
Primary Accession: O60443
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
[Gasdermin-E]: Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis (PubMed:27281216, PubMed:28459430, PubMed:33852854, PubMed:35594856, PubMed:36607699). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:28459430).
Other Names:
Gasdermin-E, Inversely correlated with estrogen receptor expression 1, ICERE-1, Non-syndromic hearing impairment protein 5, Gasdermin-E, N-terminal, GSDME-NT, Gasdermin-E, C-terminal, GSDME-CT, GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}
Gene ID: 1687
Primary Accession: O60443
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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