Gastrin Receptor polyclonal, anti-human, mouse, rat, dog

Gastrin Receptor polyclonal, anti-human, mouse, rat, dog

€422.00
In stock
SKU
250659
Catalog Nr.: 250659
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Protein Family: Receptors and Channels

Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction

Description:
The gastrin receptor (CKK-B) is a receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. CKK-B mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Alternate Names: Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P32239

Antigen: KLH-conjugated synthetic peptide encompassing the center region of human gastrin receptor.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Phieler J. et al. 2013. The Journal of Immunology. doi:10.4049. PMID#24043887. The Complement Anaphylatoxin C5a Receptor Contributes to Obese Adipose Tissue Inflammation and Insulin Resistance.
[2] Afroz A. et al. 2013. Thesis. Norwegian Master of Science in Molecular Medicine
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