GATA-3 (phospho Ser308) rabbit polyclonal, anti-human, mouse

Backgroud: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,

Synonyms: GATA3, Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3

Gene Name: GATA3

Gene ID: 2625

SwissProt ID: P23771

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.