GATA2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GATA2(GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

Description:
Rabbit IgG polyclonal antibody for Endothelial transcription factor GATA-2 (GATA2) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
DCML antibody, Endothelial transcription factor GATA 2 antibody, Endothelial transcription factor GATA-2 antibody, Endothelial transcription factor GATA2 antibody, FLJ45948 antibody, GATA 2 antibody, GATA Binding Protein 2 antibody, GATA-binding protein 2 antibody, Gata2 antibody, GATA2_HUMAN antibody, MGC2306 antibody, MONOMAC antibody, NFE 1B antibody, NFE1B antibody, OTTHUMP00000216240 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human GATA2(46-60aa DVFFNHLDSQGNPYY), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human GATA2(46-60aa DVFFNHLDSQGNPYY), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.