GATA3 (Phospho-S308) polyclonal, anti-human

Background:
GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.

Alternative Name:
GATA3, GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-binding factor 3, Gata3, GATA3, HDR, HDRS, MGC2346, MGC5199, MGC5445, Trans acting T cell specific transcription factor GATA 3, Trans-acting T-cell-specific transcription factor GATA-3,

Application Dilution:
WB:1:1,000-1:2,000
IHC:1:50-1:200

Specificity: GATA3 (Phospho-S308) polyclonal antibody detects endogenous levels of GATA3 protein only when phosphorylated at S308.

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser308 of human GATA3.

MW: 48 kDa

Swiss-Prot: P23771(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.