GATA3 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.

Description:
Rabbit IgG polyclonal antibody for Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) detection. Tested with WB in Human, Rat.

Synonyms:
GATA 3 antibody, GATA binding factor 3 antibody, GATA binding protein 3 antibody, GATA-binding factor 3 antibody, Gata3 antibody, GATA3_HUMAN antibody, HDR antibody, HDRS antibody, MGC2346 antibody, MGC5199 antibody, MGC5445 antibody, Trans acting T cell specific transcription factor GATA 3 antibody, Trans-acting T-cell-specific transcription factor GATA-3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.