GATA3 Polyclonal Antibody

Background:
GATA3 is a transcriptional factor that binds to the enhancer elements of all 4 T-cell antigen receptor genes. GATA3 is highly expressed in naive, freshly activated cells and Th2 lineage cells and thought to be necessary and sufficient for Th2 cytokine gene expression. GATA3 and TBET interfer with each other to regulate gene expression.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Immunology, Stem Cells

Synonyms:
GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-binding factor 3, Gata3, GATA3, HDR, HDRS, MGC2346, MGC5199, MGC5445, Trans acting T cell specific transcription factor GATA 3, Trans-acting T-cell-specific transcription factor GATA-3

Immunogen: Synthetic peptide of human GATA3

Swissprot: P23771
Gene Accession: NP002042

Calculated MW: 48 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.