GATM polyclonal, anti-human, mouse, rat

Background:
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Synonyms: AGAT, AT, CCDS3

Cellular Location: Cytoplasm Intermembrane side Mitochondrion inner membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human GATM

Gene Symbol: GATM

Gene ID: 2628

Swiss prot: P50440

Calculated MW: 48kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.