GATM Polyclonal Antibody

Background:
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
GATM, AGAT, AT, CCDS3

Immunogen: Recombinant fusion protein of human GATM (NP_001473.1).

Swissprot: P50440
Gene ID: 2628

Calculated MW: 44 kDa/48 kDa
Observed MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.