GATM Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis| whereby it catalyzes the transfer of a guanido group from L-arginine to glycine| resulting in guanidinoacetic acid| the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency| an inborn error of creatine synthesis characterized by mental retardation| language impairment| and behavioral disorders.

Research Area: Metabolism, Signal transduction

Synonyms: GATM

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year