GBA polyclonal, anti-human

Background:
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Synonyms: GBA1, GCB, GLUC

Cellular Location: Lumenal side Lysosome membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human GBA

Gene Symbol: GBA

Gene ID: 2629

Swiss prot: P04062

Calculated MW: 60kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.