GBA Polyclonal Antibody

Background:
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Neuroscience, Signal transduction

Synonyms:
GBA, GBA1, GCB, GLUC

Immunogen: Recombinant fusion protein of human GBA (NP_000148.2).

Swissprot: P04062
Gene ID: 2629

Calculated MW: 29 kDa/50 kDa/54 kDa/57 kDa/59 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.