GBDR1 (R126) polyclonal, anti-human
€305.00
In stock
SKU
BS9166
Background:
GBDR1 (glialblastoma cell differentiation-related protein 1), also known as UBAC1 (ubiquitin-associated domain-containing protein 1), KPC2 or UBADC1, is a 405 amino acid protein that localizes to the cytoplasm and contains one ubiquitin-like domain, one STI1 domain and two UBA domains. Expressed ubiquitously with highest expression in heart and skeletal muscle, GBDR1 functions as a non-catalytic subunit of the KPC E3 ubiquitin-protein ligase complex, of which RNF123 is the catalytic subunit. Existing as a critical component of the KPC complex, GBDR1 is essential for the ubiquitination and proteasome-mediated degradation of p27 during the G1 phase of the cell cycle. The gene encoding GBDR1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
Alternative Name:
Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2, UBAC1, GBDR1, KPC2, UBADC1
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: GBDR1 (R126) polyclonal antibody detects endogenous levels of GBDR1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 90-138 of Human GBDR1.
MW: ~ 45 kDa
Swis Prot.: Q9BSL1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GBDR1 (glialblastoma cell differentiation-related protein 1), also known as UBAC1 (ubiquitin-associated domain-containing protein 1), KPC2 or UBADC1, is a 405 amino acid protein that localizes to the cytoplasm and contains one ubiquitin-like domain, one STI1 domain and two UBA domains. Expressed ubiquitously with highest expression in heart and skeletal muscle, GBDR1 functions as a non-catalytic subunit of the KPC E3 ubiquitin-protein ligase complex, of which RNF123 is the catalytic subunit. Existing as a critical component of the KPC complex, GBDR1 is essential for the ubiquitination and proteasome-mediated degradation of p27 during the G1 phase of the cell cycle. The gene encoding GBDR1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
Alternative Name:
Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2, UBAC1, GBDR1, KPC2, UBADC1
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: GBDR1 (R126) polyclonal antibody detects endogenous levels of GBDR1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 90-138 of Human GBDR1.
MW: ~ 45 kDa
Swis Prot.: Q9BSL1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review