GBF1 Polyclonal Antibody

Background:
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.

Research Area: Cancer, Signal Transduction

Synonyms:
GBF1, ARF1GEF

Immunogen: Recombinant fusion protein of human GBF1 (NP_004184.1).

Swissprot: Q92538
Gene ID: 8729

Calculated MW: 206 kDa
Observed MW: 260 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.