GBP1 polyclonal, anti-human

Description: Rabbit IgG polyclonal antibody for Guanylate-binding protein 1(GBP1) detection. Tested with WB in Human.Protein Name: Guanylate-binding protein 1

Protein Function:
Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. .

Other Names: Guanylate-binding protein 1, 3.6.5.-, GTP-binding protein 1, GBP-1, HuGBP-1, Guanine nucleotide-binding protein 1, Interferon-induced guanylate-binding protein 1, GBP1

Subcellular Localization: Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor.

Gene ID: 2633

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GBP1(566-589aa QKESRIMKNEIQDLQTKMRRRKAC).

Calculated MW: 67931

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.