GC monoclonal(Center) (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2180a
Catalog Number: AC-AM2180a
Size: 100 µl
Isotype: mouse IgM
Clone Name: 660CT8.6.6.2
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgM
Clone Name: 660CT8.6.6.2
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Other Names:
Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, GBA, GC, GLUC
Target/Specificity:
This GC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
Antigen Region:
337-365
Antigen Type: Synthetic Peptide
Gene Name: GBA1 (HGNC:4177)
Gene ID: 2629
Primary Accession: P04062
NCBI Accession: NP_000148.2;NP_001005741.1;NP_001005742.1
Other Accession: Q70KH2; Q2KHZ8; NP_000148.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Other Names:
Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, GBA, GC, GLUC
Target/Specificity:
This GC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
Antigen Region:
337-365
Antigen Type: Synthetic Peptide
Gene Name: GBA1 (HGNC:4177)
Gene ID: 2629
Primary Accession: P04062
NCBI Accession: NP_000148.2;NP_001005741.1;NP_001005742.1
Other Accession: Q70KH2; Q2KHZ8; NP_000148.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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