GCG Polyclonal Antibody

Background:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Research Area: Cancer, Metabolism, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
GCG, GLP 2, GLP1, GLP2, glucagon, GRPP, Glucagon like peptide 1, GRPP Oxyntomodulin, OXM, Proglucagon

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Glucagon

Swissprot: P55095,P06883

Calculated MW: 21 kDa
Observed MW: 25 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.