GCKR Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8143a
Background:
GCKR belongs to the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8143a was selected from the N-term region of human GCKR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
GCKR belongs to the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8143a was selected from the N-term region of human GCKR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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