GCKR Blocking Peptide (N-Term)
€363.00
In stock
SKU
AC-BP21610a
Background:
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
The synthetic peptide sequence is selected from aa 87-100 of HUMAN GCKR
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
The synthetic peptide sequence is selected from aa 87-100 of HUMAN GCKR
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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