GCKR polyclonal antibody, anti-human, mouse, rat

Background:
GCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Research Area: Signal Transduction, Metabolism

Synonyms: GCKR, Glucokinase regulatory protein, Glucokinase regulator

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year