GCKR Polyclonal Antibody

Background:
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
FGQTL5, GCK, GCKR, GCKR, GKRP, GLRE, glucokinase (hexokinase 4) regulator, Glucokinase, Glucokinase regulator, Glucokinase regulatory protein, Hexokinase 4 regulator, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HK IV, HK4, OTTHUMP00000158533

Immunogen: Synthetic peptide of human GCKR

Swissprot: Q14397
Gene Accession: NP_001477

Calculated MW: 69 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6340/sc-11416