GCKR polyclonal (N-Term), anti-human
€0.00
In stock
SKU
AC-AP21592a
Catalog Number: AC-AP21592a
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53114
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53114
Applications: WB
Datasheet
Request Information
Background:
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
This GCKR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from human GCKR.
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
Target/Specificity:
This GCKR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from human GCKR.
Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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