GCKR polyclonal (N-term), anti-human

GCKR polyclonal (N-term), anti-human

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In stock
SKU
AC-AP8143a
Catalog Number: AC-AP8143a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3929
Applications: WB, IHC-P
Datasheet

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Background:
GCKR belongs to the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. The GCKR gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR

Target/Specificity:
This GCKR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GCKR.

Antigen Region:
1-30

Antigen Type: Synthetic Peptide

Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
NCBI Accession: NP_001477.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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