GCKR polyclonal (N-Term), anti-mouse, rat

Background:
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Other Names:
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR

Target/Specificity:
This GCKR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from human GCKR.

Gene Name: GCKR {ECO:0000303|PubMed:8589523, ECO:0000312|HGNC:HGNC:4196}
Gene ID: 2646
Primary Accession: Q14397
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.