GCLC antibody (clone 3H1), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT2176a
Catalog Number: AC-AT2176a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT2176a-GCLC-Antibody-monoclonal-M01">Request Information AC-AT2176a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT2176a-GCLC-Antibody-monoclonal-M01">Request Information AC-AT2176a">Request Information
Background:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
Other Names:
Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCLC, GLCL, GLCLC
Antigen Type:
Recombinant Protein
Gene Name: GCLC (HGNC:4311)
Gene ID: 2729
NCBI Accession: NP_001184044.1;NP_001489.1
Primary Accession: P48506
Other Accession: NM_001498
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
Other Names:
Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCLC, GLCL, GLCLC
Antigen Type:
Recombinant Protein
Gene Name: GCLC (HGNC:4311)
Gene ID: 2729
NCBI Accession: NP_001184044.1;NP_001489.1
Primary Accession: P48506
Other Accession: NM_001498
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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