GCNT1 polyclonal (Center), anti-human, mouse

GCNT1 polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP2404a
Catalog Number: AC-AP2404a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB4836
Applications: WB, IHC-P
Datasheet

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Background:
Glycosylation is one of the most universal but at the same time complex protein modifications. Modification with sugar moeties can be both co- translational and post- translational, occurring in the endoplasmatic reticulum and golgi. Three different forms of glycosylation can be distinguished: N-linked oligosaccharides, O-linked oligosaccharides and glycosyl- phosphatidylinositol (GPI-) anchors. Glycosylation results in thousands of distinct, bioactive glycoproteins resident throughout the cell that strongly determine protein-protein, carbohydrate-protein, membrane, and adhesion properties. Diseases associated with glycosylation defects include Congenital disorders of glycosylation, (CDG), also known as carbohydrate deficient glycoprotein syndromes, and diseases associated with advanced aging.

Other Names:
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2

Target/Specificity:
This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human GCNT1.

Antigen Region:
88-117

Antigen Type: Synthetic Peptide

Gene Name: GCNT1
Gene ID: 2650
Primary Accession: Q02742
NCBI Accession: NP_001091102.1;NP_001091103.1;NP_001091104.1;NP_001091105.1;NP_001481.2
Other Accession: NP_001481
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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