GCNT2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP18452c
Catalog Number: AC-AP18452c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38784
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38784
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Target/Specificity:
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the Central region of human GCNT2.
Antigen Region:
213-240
Antigen Type: Synthetic Peptide
Gene Name: GCNT2
Gene ID: 2651
Primary Accession: Q8N0V5
NCBI Accession: NP_663624.1
Other Accession: NP_663624.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Target/Specificity:
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the Central region of human GCNT2.
Antigen Region:
213-240
Antigen Type: Synthetic Peptide
Gene Name: GCNT2
Gene ID: 2651
Primary Accession: Q8N0V5
NCBI Accession: NP_663624.1
Other Accession: NP_663624.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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