GCP4 polyclonal antibody, anti-human, mouse
€0.00
In stock
SKU
BT-AP03517
Catalog Number: BT-AP03517
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse
Application(s): WB, IHC-p, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse
Application(s): WB, IHC-p, ELISA
Datasheet
Request Information
Background:
TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
Research Area: Others
Synonyms: TUBGCP4, 76P, GCP4, Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
Research Area: Others
Synonyms: TUBGCP4, 76P, GCP4, Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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